Peptide glossary
GHK-Cu
GHK-Cu is a tripeptide of glycine, histidine and lysine bound to a copper ion. It activates fibroblasts to build collagen I, III and elastin while slowing collagen-degrading enzymes.
- INCI name
- Copper Tripeptide-1
- Also known as
- Copper tripeptide-1, Copper peptide, Glycyl-L-histidyl-L-lysine copper
Mechanism
The peptide carries copper into the dermis as a cofactor, where it influences the expression of more than 4,000 genes — mainly those governing wound healing, collagen synthesis and antioxidant defence.
How to use and layer it
- Two to three drops on cleansed skin in the evening
- Not in the same step as high-dose vitamin C or strong acids
- Pairs well with niacinamide, hyaluronic acid and panthenol
- Light-protected packaging, because the copper complex is sensitive
All of it in one formula
EDNF25070922 combines GHK-Cu, bio microneedling, the 5-peptide complex and 24K gold in a single serum.
View the serumFrequently asked questions
- What is GHK-Cu?
- GHK-Cu is copper tripeptide-1: a three-amino-acid peptide that carries a copper ion into the skin and stimulates collagen production there.
- What is GHK-Cu called on the INCI list?
- Copper Tripeptide-1. If it appears in the upper third of the INCI list, an effective concentration is likely.