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Peptide glossary

Signal peptide

A signal peptide is a peptide that prompts skin cells to produce structural proteins. It mimics the fragments released when collagen breaks down, which skin reads as a repair order.

Also known as
Matrikine, Collagen signal peptide
Signal peptide

Typical signal peptides

  • GHK-Cu (copper tripeptide-1): collagen I and III, elastin, wound healing
  • Palmitoyl pentapeptide-4 (Matrixyl): collagen I and IV, hyaluronic acid
  • Palmitoyl tripeptide-1: collagen signalling in the dermis

How they differ from other peptide classes

Signal peptides build. Neurotransmitter-inhibiting peptides such as Argireline or SNAP-8 relax expression instead. The two groups act at different points and can be combined.

All of it in one formula

EDNF25070922 combines GHK-Cu, bio microneedling, the 5-peptide complex and 24K gold in a single serum.

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Frequently asked questions

What is a signal peptide?
A signal peptide is a short peptide that prompts fibroblasts in the skin to build new collagen, elastin or hyaluronic acid.
Which signal peptides have the best evidence?
GHK-Cu is the most studied signal peptide, followed by palmitoyl pentapeptide-4 (Matrixyl).

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