Peptide glossary
SNAP-8 (Acetyl Octapeptide-3)
SNAP-8 is acetyl octapeptide-3, an eight-amino-acid peptide developed as the successor to Argireline. It dampens SNARE complex formation and with it muscle contraction in expression areas.
- INCI name
- Acetyl Octapeptide-3
- Also known as
- Acetyl octapeptide-3

Difference from Argireline
SNAP-8 carries two extra amino acids and binds more stably to the SNAP-25 fragment. Formulas often use both together because their effects on forehead and eye area complement each other.
How to use it
- In the evening serum step, before moisturiser
- Visible effect on expression lines after 4 to 8 weeks
- Well tolerated, no photosensitivity
- Best combined with GHK-Cu for collagen building
All of it in one formula
EDNF25070922 combines GHK-Cu, bio microneedling, the 5-peptide complex and 24K gold in a single serum.
View the serumFrequently asked questions
- What is SNAP-8?
- SNAP-8 is acetyl octapeptide-3, an eight-amino-acid peptide that topically dampens the signal to expression muscles so expression lines look softer.
- Is SNAP-8 stronger than Argireline?
- SNAP-8 binds more stably on the same pathway and is considered more potent. In practice the two are often combined.
Keep reading
Straight to the details
Jump into the buying criteria, tolerance notes and FAQs of the matching ingredient pages.