Peptide glossary
SNAP-8 (Acetyl Octapeptide-3)
SNAP-8 is acetyl octapeptide-3, an eight-amino-acid peptide developed as the successor to Argireline. It dampens SNARE complex formation and with it muscle contraction in expression areas.
- INCI name
- Acetyl Octapeptide-3
- Also known as
- Acetyl octapeptide-3

Difference from Argireline
SNAP-8 carries two extra amino acids and binds more stably to the SNAP-25 fragment. Formulas often use both together because their effects on forehead and eye area complement each other.
How to use it
- In the evening serum step, before moisturiser
- Visible effect on expression lines after 4 to 8 weeks
- Well tolerated, no photosensitivity
- Best combined with GHK-Cu for collagen building
All of it in one formula
EDNF25070922 combines GHK-Cu, bio microneedling, the 5-peptide complex and 24K gold in a single serum.
View the serumFrequently asked questions
- What is SNAP-8?
- SNAP-8 is acetyl octapeptide-3, an eight-amino-acid peptide that topically dampens the signal to expression muscles so expression lines look softer.
- Is SNAP-8 stronger than Argireline?
- SNAP-8 binds more stably on the same pathway and is considered more potent. In practice the two are often combined.