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Peptide glossary

SNAP-8 (Acetyl Octapeptide-3)

SNAP-8 is acetyl octapeptide-3, an eight-amino-acid peptide developed as the successor to Argireline. It dampens SNARE complex formation and with it muscle contraction in expression areas.

INCI name
Acetyl Octapeptide-3
Also known as
Acetyl octapeptide-3
SNAP-8 (Acetyl Octapeptide-3)

Difference from Argireline

SNAP-8 carries two extra amino acids and binds more stably to the SNAP-25 fragment. Formulas often use both together because their effects on forehead and eye area complement each other.

How to use it

  • In the evening serum step, before moisturiser
  • Visible effect on expression lines after 4 to 8 weeks
  • Well tolerated, no photosensitivity
  • Best combined with GHK-Cu for collagen building

All of it in one formula

EDNF25070922 combines GHK-Cu, bio microneedling, the 5-peptide complex and 24K gold in a single serum.

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Frequently asked questions

What is SNAP-8?
SNAP-8 is acetyl octapeptide-3, an eight-amino-acid peptide that topically dampens the signal to expression muscles so expression lines look softer.
Is SNAP-8 stronger than Argireline?
SNAP-8 binds more stably on the same pathway and is considered more potent. In practice the two are often combined.

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