Argireline is the brand name of acetyl hexapeptide-8, a six-amino-acid peptide that topically weakens muscle contraction in expression areas so fine lines look softer.

Is Argireline the same as Botox?

No. Argireline targets the same signalling pathway but works topically, far more mildly, without injection and fully reversibly.

Peptide glossary

Argireline (Acetyl Hexapeptide-8)

Argireline is the trade name for acetyl hexapeptide-8, a hexapeptide that dampens neurotransmitter release at the muscle end plate. Expression lines look softer as a result.

INCI name: Acetyl Hexapeptide-8
Also known as: Acetyl hexapeptide-8, Acetyl hexapeptide-3, Botox peptide

How it works

The peptide acts on the SNAP-25 complex — the same target as botulinum toxin, but far weaker and applied topically. It softens surface muscle contraction with no injection and no downtime.

Argireline vs Botox

Topical instead of injected — no medical procedure
Gradual and reversible, visible over 4 to 8 weeks
Best for forehead, frown lines and crow's feet
Pairs well with GHK-Cu: relaxation plus collagen building

All of it in one formula

EDNF25070922 combines GHK-Cu, bio microneedling, the 5-peptide complex and 24K gold in a single serum.

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Frequently asked questions

What is Argireline?: Argireline is the brand name of acetyl hexapeptide-8, a six-amino-acid peptide that topically weakens muscle contraction in expression areas so fine lines look softer.
Is Argireline the same as Botox?: No. Argireline targets the same signalling pathway but works topically, far more mildly, without injection and fully reversibly.

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