Peptide glossary
Argireline (Acetyl Hexapeptide-8)
Argireline is the trade name for acetyl hexapeptide-8, a hexapeptide that dampens neurotransmitter release at the muscle end plate. Expression lines look softer as a result.
- INCI name
- Acetyl Hexapeptide-8
- Also known as
- Acetyl hexapeptide-8, Acetyl hexapeptide-3, Botox peptide

How it works
The peptide acts on the SNAP-25 complex — the same target as botulinum toxin, but far weaker and applied topically. It softens surface muscle contraction with no injection and no downtime.
Argireline vs Botox
- Topical instead of injected — no medical procedure
- Gradual and reversible, visible over 4 to 8 weeks
- Best for forehead, frown lines and crow's feet
- Pairs well with GHK-Cu: relaxation plus collagen building
All of it in one formula
EDNF25070922 combines GHK-Cu, bio microneedling, the 5-peptide complex and 24K gold in a single serum.
View the serumFrequently asked questions
- What is Argireline?
- Argireline is the brand name of acetyl hexapeptide-8, a six-amino-acid peptide that topically weakens muscle contraction in expression areas so fine lines look softer.
- Is Argireline the same as Botox?
- No. Argireline targets the same signalling pathway but works topically, far more mildly, without injection and fully reversibly.